Dr. Lucy Osborne received her doctoral degree from The University of London, England and completed post-doctoral training in human genetics with Prof. Lap-Chee Tsui at the Hospital for Sick Children. She was appointed at the University of Toronto in 1999 and is currently a Professor in Medicine and Molecular Genetics, with a laboratory on campus in the Medical Sciences Building. She has received the Andrew Sass-Kortsak post-doctoral award, a CIHR New Investigator Scholarship and a Premier’s Research Excellence Award, and her research is funded by CIHR and the Simon’s Foundation Autism Research Initiative.
The major focus of Dr. Osborne’s research is chromosome rearrangements of human chromosome 7q11.23, with the aim of understanding the molecular basis of the resulting neurodevelopmental disorders. Her lab is at the forefront of research into the deletion disorder Williams syndrome, as well as it’s reciprocal duplication disorder, and has helped elucidate the range of complex chromosomal rearrangements associated with this part of chromosome 7. Osborne and her team are currently using both human participants and animal models to probe the molecular and cellular bases of cognitive and behavioural aspects of these syndromes.